14-3-3 zeta anticorps (AA 48-245)

N° du produit ABIN5027007

Cet anticorps Lapin Polyclonal détecte spécifiquement 14-3-3 zeta dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour 14-3-3 zeta anticorps (AA 48-245) (ABIN5027007)

Antigène: 14-3-3 zeta (YWHAZ)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 zeta est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-14-3-3 zeta anticorps

Épitope: AA 48-245

Purification: Protein A Chromatography

Immunogène: A partial length recombinant 14-3-3 Zeta protein (amino acids 48-245) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur 14-3-3 zeta

Antigène: 14-3-3 zeta (YWHAZ)

Autre désignation: 14-3-3 Zeta

Sujet: 14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).

Poids moléculaire: 28 kDa

ID gène: 7534

UniProt: P63104

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location