CD33 anticorps (AA 28-320)

N° du produit ABIN5027091

Cet anticorps Souris Monoclonal détecte spécifiquement CD33 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour CD33 anticorps (AA 28-320) (ABIN5027091)

Antigène: CD33

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ABM29D3

Détail du produit anti-CD33 anticorps

Épitope: AA 28-320

Purification: Protein G Chromatography

Immunogène: A partial length recombinant CD33 protein (amino acids 28-320) was used as the immunogen for this antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CD33

Antigène: CD33

Autre désignation: CD33

Sujet: CD33 is a member of the SIGLEC (Sialic Acid-Binding Ig-Like Lectin) family of receptors, and the gene comprises seven coding exons. Exon 2 encodes the canonical IgV domain, exon 4 encodes the IgC structural domain, and exons 6 and 7 encode cytosolic ITIMs (Immunotyrosine Inhibitory Motifs). CD33 acts as a cell surface antigen which is expressed on normal myeloid cells and CD34+ blasts in AML (Acute Myeloid Leukemia). The antigen serves as a target of GO (Gemtuzumab/Ozogamicin), which exerts anti-leukemic effects in refractory AML.

Poids moléculaire: 39 kDa

ID gène: 945

UniProt: P20138