Cyclin D1 anticorps (AA 108-322)
Aperçu rapide pour Cyclin D1 anticorps (AA 108-322) (ABIN5027124)
Antigène
Voir toutes Cyclin D1 (CCND1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 108-322
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Purification
- Protein G Chromatography
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Immunogène
- A partial length recombinant Cyclin D1 protein (amino acids 108-322) was used as the immunogen for this antibody.
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Isotype
- IgG2a kappa
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anti-Cyclin D1 (CCND1) (AA 61-110) antibody
CCND1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Mouton WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyKO Validated CCND1 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Monoclonal unconjugated
anti-Cyclin D1 (CCND1) (AA 68-97) antibodyCCND1 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal RB8066 unconjugated
anti-Cyclin D1 (CCND1) (AA 167-295) antibodyCCND1 Reactivité: Humain IHC, ELISA, FACS, ICC Hôte: Souris Monoclonal 3B6G3 unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 Reactivité: Humain, Souris WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 1F7F5 unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Cyclin D1 (CCND1) (C-Term) antibodyCCND1 Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Cyclin D1 (CCND1) antibodyCCND1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, FACS, IF, StM Hôte: Souris Monoclonal DCS-6 unconjugated
anti-Cyclin D1 (CCND1) (AA 1-295) antibodyCCND1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- IHC: 5-10 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Cyclin D1 (CCND1)
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Autre désignation
- Cyclin D1
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Sujet
- Cyclin D1 (CCND1) is an important positive regulator of the G1/S phase of the cell cycle. It regulate cell cycle transition from G1 phase to S phase It is a well-established human oncogene which is frequently amplified or overexpressed in cancers (25409185). Cyclin D1b is one of two proteins translated from Cyclin D1 transcripts (isoforms a and b) that are generated due to gene polymorphism. Low Cyclin D1b expression in cervical cancer tissue, with an expression level in moderately or poorly differentiated tissues was significantly lower than that in well-differentiated tissues (25120779). Diseases associated with CCND1 include multiple myeloma and mantle cell lymphoma.
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ID gène
- 23582
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UniProt
- O95273
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Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
Antigène
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