IDH1 anticorps (AA 198-414)

N° du produit ABIN5027284

L’anticorps Souris Monoclonal anti-IDH1 a été validé pour IHC. Il convient pour détecter IDH1 dans des échantillons de Humain.

Aperçu rapide pour IDH1 anticorps (AA 198-414) (ABIN5027284)

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDH1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: ABM44B3

Détail du produit anti-IDH1 anticorps

Épitope: AA 198-414

Purification: Protein G Chromatography

Immunogène: A partial length recombinant IDH1 protein (amino acids 198-414) was used as the immunogen for this antibody

Isotype: IgG2a kappa

Information d'application

Indications d'application: IHC: 5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur IDH1

Antigène: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Autre désignation: IDH1

Sujet: Isocitrate dehydrogenase 1 (IDH1) is a dimeric cytosolic NADP-dependent dehydrogenase that catalyzes decarboxylation of isocitrate into alpha-ketoglutarate. It belongs to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). It serves a significant role in cytoplasmic NADPH production. It is found in the cytoplasm and peroxisomes. IDH1 is of great importance in cell metabolism and energy conversion. Mutations in IDH1 are found in a somatic mosaic fashion in patients with multiple enchondromas.

ID gène: 3417

UniProt: O75874

Pathways: L'effet Warburg