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MYD88 anticorps (AA 1-200)
MYD88
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5027378
Détail du produit anti-MYD88 anticorps
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Antigène
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MYD88
(Myeloid Differentiation Primary Response Gene (88) (MYD88))
Épitope
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AA 1-200
Reactivité
Toutes les réactivités sur MYD88 Anticorps
Humain
Hôte
Toutes les hôtes sur MYD88 Anticorps
Lapin
Clonalité
Toutes les clonalités sur MYD88 Anticorps
Polyclonal
Conjugué
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Cet anticorp MYD88 est non-conjugé
Application
Tous les applications à travers MYD88 Anticorps.
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogène
A partial length recombinant MyD88 protein (amino acids 1-200) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
WB: 4-6 μg/mL
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Détails sur MYD88
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Antigène
MYD88
(Myeloid Differentiation Primary Response Gene (88) (MYD88))
Autre désignation
MyD88 (MYD88 Produits )
Synonymes
anticorps MYD88D, anticorps XMyD88, anticorps myd88d, anticorps MGC84928, anticorps CG2078, anticorps DMMYD88, anticorps DmMyD88, anticorps DmMyd88, anticorps Dmel\\CG2078, anticorps EP(2)2535, anticorps Kra, anticorps LD20892, anticorps MYD88, anticorps MyD88, anticorps Myd88F, anticorps dMyD88, anticorps dMyd88, anticorps kra, anticorps myd88, anticorps zgc:103541, anticorps GB12344, anticorps NV10640, anticorps myd88-a, anticorps myd88-b, anticorps myeloid differentiation primary response 88, anticorps myeloid differentiation primary response 88 S homeolog, anticorps myeloid differentiation primary response gene 88, anticorps CG2078 gene product from transcript CG2078-RB, anticorps myeloid differentiation primary response protein MyD88-A, anticorps myeloid differentiation primary response protein MyD88, anticorps myeloid differentiation factor 88, anticorps myeloid differentiation primary response 88 L homeolog, anticorps MYD88, anticorps myd88.S, anticorps Myd88, anticorps myd88, anticorps LOC413194, anticorps LOC100118553, anticorps LOC575153, anticorps myd88.L
Sujet
MyD88 (Myeloid differentiation factor) is an essential adaptor molecule in all TLR (Toll-like receptor) signaling pathways except TLR3. MyD88 is composed of an N-terminal (Death Domain) and a highly conserved C-terminal TIR (Toll/interleukin-1 Receptor) domain. It is found to stimulate IL-1R/IL18R-mediated signaling. MyD88-dependent signaling is also important in the regulation of innate as well as acquired immunity, in particular, T-cell responses, to various microbial pathogens. After activation of TLRs, MyD88 is phosphorylated and subsequently recruits IRAKs (IL-1R Associated Kinases) and other downstream proteins such as TRAF6, finally resulting in activation of the NF-kappaB (nuclear factor kappa B) pathway.
Poids moléculaire
32 kDa
ID gène
4615
UniProt
Q99836
Pathways
Signalisation NF-kappaB , Signalisation TLR , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Toll-Like Receptors Cascades
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