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NLRP3 anticorps (AA 1-200)
NLRP3
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5027649
Détail du produit anti-NLRP3 anticorps
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Antigène
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NLRP3
(NLR Family, Pyrin Domain Containing 3 (NLRP3))
Épitope
Tous les épitopes à travers NLRP3 Anticorps.
AA 1-200
Reactivité
Toutes les réactivités sur NLRP3 Anticorps
Humain
Hôte
Toutes les hôtes sur NLRP3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur NLRP3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NLRP3 Anticorps
Cet anticorp NLRP3 est non-conjugé
Application
Tous les applications à travers NLRP3 Anticorps.
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogène
A partial recombinant NALP3 protein (amino acids 1-200) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 15-120) antibody
NLRP3
Reactivité: Humain, Souris, Rat, Chien
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
WB: 2-4 μg/mL
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Détails sur NLRP3
(cache)
Antigène
NLRP3
(NLR Family, Pyrin Domain Containing 3 (NLRP3))
Autre désignation
NALP3/CIAS1/Cryopyrin/PYPAF1 (NLRP3 Produits )
Synonymes
anticorps CIAS1, anticorps Nalp3, anticorps avp, anticorps cias1, anticorps nalp3, anticorps pypaf1, anticorps agtavprl, anticorps AGTAVPRL, anticorps AII, anticorps AVP, anticorps C1orf7, anticorps CLR1.1, anticorps FCAS, anticorps FCU, anticorps MWS, anticorps NALP3, anticorps PYPAF1, anticorps AII/AVP, anticorps Cias1, anticorps Mmig1, anticorps Pypaf1, anticorps NLR family pyrin domain containing-like, anticorps NLR family pyrin domain containing 3, anticorps NLR family, pyrin domain containing 3 L homeolog, anticorps NLR family, pyrin domain containing 3, anticorps NLRPL, anticorps NLRP3, anticorps nlrp3.L, anticorps Nlrp3
Sujet
NALP3 (NACHT, LRR and PYD domains-containing protein 3), otherwise known as cryopyrin, is a member of the NLR (Nod-like-receptors) family. This is a pyrin-like protein, having N-terminal CARD or pyrin domains needed for homotypic protein-protein interaction, an intermediate nucleotide binding self-oligomerization NACHT domain and a C-terminal domain containing leucine-rich repeats (LRRs). NALP3 is a key component of innate immunity and its expression is restricted to immune cells and chondrocytes. It interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappa signaling, and it plays an important role in the regulation of inflammation, the immune response, and apoptosis.
Poids moléculaire
114 kDa
ID gène
114548
UniProt
Q96P20
Pathways
Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Endopeptidase Activity , Inflammasome
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