Angiopoietin 1 anticorps (C-Term)

N° du produit ABIN504734

L’anticorps Lapin Polyclonal anti-Angiopoietin 1 a été validé pour WB et IHC. Il convient pour détecter Angiopoietin 1 dans des échantillons de Humain, Souris et Lapin.

Aperçu rapide pour Angiopoietin 1 anticorps (C-Term) (ABIN504734)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: C-Term

Réactivité croisée: Chien, Humain, Lapin, Rat (Rattus)

Purification: affinity purified

Immunogène: C-terminal sequence of human Angiopoietin-1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin-1

Sujet: Angiopoietin 1 is one of the Angiopoietin (Ang) family of growth factors. It binds and activates the TIE2 receptor tyrosine kinase by inducing its tyrosine phosphorylation. It is implicated in endothelial developmental processes later and distinct from that of VEGF. The structure of angiopoietin 1 differs from that of known angiogenic factors or other ligands for receptor tyrosine kinases. Angiopoietin 1 appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. It also mediates blood vessel maturation/stability and it may play an important role in the heart early development. Angiopoietin 1 may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart.

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process