HLA-ABC anticorps (APC)

N° du produit ABIN5067853

Cet anticorps Souris Monoclonal détecte spécifiquement HLA-ABC dans FACS. Il présente une réactivité envers Humain, Babouin, Cynomolgus et Macaque rhésus.

Aperçu rapide pour HLA-ABC anticorps (APC) (ABIN5067853)

Antigène: HLA-ABC

Reactivité: Humain, Babouin, Cynomolgus, Macaque rhésus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-ABC est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: W6-32

Détail du produit anti-HLA-ABC anticorps (APC)

Fonction: Anti-HLA-ABC APC Antibody

Attributs du produit: Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.

Purification: Purified

Pureté: >95 %

Immunogène: Human Leukocytes

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA-ABC

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints