EIF2AK2 anticorps (AA 1-100)

N° du produit ABIN519273

Cité dans 3 publications. Cet anticorps anti-EIF2AK2 Monoclonal Souris (Clone 1D11) (ABIN519273) détecte spécifiquement EIF2AK2 dans WB, ELISA, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EIF2AK2 anticorps (AA 1-100) (ABIN519273)

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF2AK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1D11

Détail du produit anti-EIF2AK2 anticorps

Épitope: AA 1-100

Fonction: Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.

Séquence: MAGDLSAGFF MEELNTYRQK QGVVLKYQEL PNSGPPHDRR FTFQVIIDGR EFPEGEGRSK KEAKNAAAKL AVEILNKEKK AVSPLLLTTT NSSEGLSMGN

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-EIF2AK2 (ABIN519273)

Liu, Bennett, Cheng, Byrne, Reinhard, May: "PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells." dans: Blood, Vol. 121, Issue 17, pp. 3364-74, (2013) (PubMed).

Cheng, Bennett, Liu, Byrne, Stratford May: "PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis." dans: Blood cancer journal, Vol. 3, pp. e144, (2013) (PubMed).

Bennett, Carruthers, Hui, Kerney, Liu, May: "Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicin." dans: PLoS ONE, Vol. 7, Issue 9, pp. e46040, (2012) (PubMed).

Détails sur EIF2AK2

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: EIF2AK2

Sujet: Full Gene Name: eukaryotic translation initiation factor 2-alpha kinase 2
Synonyms: EIF2AK1,MGC126524,PKR,PRKR

ID gène: 5610

NCBI Accession: NM_002759

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C