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SPHK1 anticorps (AA 1-384)

SPHK1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1D6 unconjugated
N° du produit ABIN522355
  • Antigène Voir toutes SPHK1 Anticorps
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Épitope
    • 15
    • 14
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-384
    Reactivité
    • 104
    • 44
    • 38
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 96
    • 8
    • 1
    Souris
    Clonalité
    • 92
    • 13
    Monoclonal
    Conjugué
    • 55
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPHK1 est non-conjugé
    Application
    • 75
    • 45
    • 25
    • 19
    • 14
    • 13
    • 13
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA
    Fonction
    Mouse monoclonal antibody raised against a full length recombinant SPHK1.
    Séquence
    MDPAGGPRGV LPRPCRVLVL LNPRGGKGKA LQLFRSHVQP LLAEAEISFT LMLTERRNHA RELVRSEELG RWDALVVMSG DGLMHEVVNG LMERPDWETA IQKPLCSLPA GSGNALAASL NHYAGYEQVT NEDLLTNCTL LLCRRLLSPM NLLSLHTASG LRLFSVLSLA WGFIADVDLE SEKYRRLGEM RFTLGTFLLL AALRTYRGRL AYLPVGRVGS KTPASPVVVQ QGPVDAHLVP LEEPVPSHWT VVPDEDFVLV LALLHSHLGS EMFAAPMGRC AAGVMHLFYV RAGVSRAMLL RLFLAMEKGR HMEYECPYLV YVPVVAFRLE PKDGKGVFAV DGELMVSEAV QGQVHPNYFW MVSGCVEPPP SWKPQQMPPP EEPL
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    SPHK1 (AAH08040, 1 a.a. ~ 384 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1D6
    Isotype
    IgG2a
    Top Product
    Discover our top product SPHK1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Sheu, Lee, Hua, Li, Lai, Lee, Cheng, Chen, Chan, Chao, Chen, Chang, Lee: "LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling." dans: Oncogene, Vol. 33, Issue 11, pp. 1375-84, (2014) (PubMed).

    Böhm, Flößer, Ermler, Fender, Lüth, Kleuser, Schrör, Rauch: "Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells." dans: Cardiovascular research, Vol. 99, Issue 3, pp. 505-13, (2013) (PubMed).

    Zhang, Wang, Zhao, Di: "MiR-124 inhibits the migration and invasion of ovarian cancer cells by targeting SphK1." dans: Journal of ovarian research, Vol. 6, Issue 1, pp. 84, (2013) (PubMed).

    Schenten, Melchior, Steinckwich, Tschirhart, Bréchard: "Sphingosine kinases regulate NOX2 activity via p38 MAPK-dependent translocation of S100A8/A9." dans: Journal of leukocyte biology, Vol. 89, Issue 4, pp. 587-96, (2011) (PubMed).

    Ali-Rahmani, Hengst, Connor, Schengrund: "Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells." dans: Neurochemical research, Vol. 36, Issue 9, pp. 1687-96, (2011) (PubMed).

    Asher, Warren, Shaw, Sowter, Bali, Khan: "The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line." dans: Cancer cell international, Vol. 11, pp. 6, (2011) (PubMed).

    Schröder, Richter, Juan, Maltusch, Giegold, Quintini, Pfeilschifter, Huwiler, Radeke: "The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen." dans: Molecular immunology, Vol. 48, Issue 9-10, pp. 1139-48, (2011) (PubMed).

    Sinha, Schorn, Hochstim, Chinn, Zhu, Masood: "Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition." dans: Head & neck, Vol. 33, Issue 2, pp. 178-88, (2011) (PubMed).

    Wang, Zhang, Lin, Xu, Feng, Ding: "A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart." dans: Glycobiology, Vol. 20, Issue 4, pp. 473-84, (2010) (PubMed).

    Billich, Urtz, Reuschel, Baumruker: "Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells." dans: The international journal of biochemistry & cell biology, Vol. 41, Issue 7, pp. 1547-55, (2009) (PubMed).

    dans: (PubMed).

  • Antigène
    SPHK1 (Sphingosine Kinase 1 (SPHK1))
    Autre désignation
    SPHK1 (SPHK1 Produits)
    Synonymes
    anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1
    Sujet
    Full Gene Name: sphingosine kinase 1
    Synonyms: SPHK
    ID gène
    8877
    Pathways
    VEGF Signaling
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