SPHK1 anticorps (C-Term)

N° du produit ABIN652302

Détail du produit anti-SPHK1 anticorps

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Épitope: AA 313-343, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-343 amino acids from the C-terminal region of human SPHK1.

Clone: RB15395

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: SPHK1 (SPHK1 Produits)

Synonymes: anticorps CG1747, anticorps Dmel\\CG1747, anticorps SK1, anticorps Sphk1, anticorps SPHK1, anticorps F18E5.160, anticorps F18E5_160, anticorps sphingosine kinase 1, anticorps SPHK, anticorps 1110006G24Rik, anticorps Sk1, anticorps Spk1, anticorps Sphingosine kinase 1, anticorps sphingosine kinase 1, anticorps sphingosine kinase 1 L homeolog, anticorps Sk1, anticorps SPHK1, anticorps sphk1.L, anticorps Sphk1

Sujet: SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.

ID gène: 8877

NCBI Accession: NP_001136073, NP_001136074, NP_068807, NP_892010

UniProt: Q9NYA1

Pathways: VEGF Signaling