AIM2 anticorps (AA 1-343)

N° du produit ABIN522906

Cité dans 4 publications. Cet anticorps anti-AIM2 Polyclonal Souris (ABIN522906) détecte spécifiquement AIM2 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AIM2 anticorps (AA 1-343) (ABIN522906)

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp AIM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-AIM2 anticorps

Épitope: AA 1-343

Fonction: Mouse polyclonal antibody raised against a full-length human AIM2 protein.

Séquence: MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: AIM2 (NP_004824, 1 a.a. ~ 343 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-AIM2 (ABIN522906)

Ansari, Singh, Dutta, Veettil, Dutta, Chikoti, Lu, Everly, Chandran: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." dans: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).

Lee, Li, Gretz, Gebert, Dihlmann: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." dans: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).

Wang, Hsu, Chen, Liang, Chen, Ojcius, Tsang, Hsueh, Wu, Chang: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." dans: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).

Fernandes-Alnemri, Yu, Datta, Wu, Alnemri: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." dans: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).

Détails sur AIM2

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Autre désignation: AIM2

Sujet: Full Gene Name: absent in melanoma 2
Synonyms: PYHIN4

ID gène: 9447

NCBI Accession: NM_004833

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome