AIM2 anticorps (AA 255-354)
-
- Antigène Voir toutes AIM2 Anticorps
- AIM2 (Absent in Melanoma 2 (AIM2))
-
Épitope
- AA 255-354
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp AIM2 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from mouse AIM2
- Isotype
- IgG
- Top Product
- Discover our top product AIM2 Anticorps primaire
-
anti-Absent in Melanoma 2 (AIM2) (AA 1-195) antibody
AIM2 Reactivité: Humain WB, ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 3C4G11 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-50) antibodyAIM2 Reactivité: Humain WB, ELISA, FACS, IF Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 81-326) antibodyAIM2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibodyAIM2 Reactivité: Humain WB, FACS, IF Hôte: Lapin Polyclonal RB23659 unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-343) antibodyAIM2 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (Internal Region) antibodyAIM2 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 1-260) antibodyAIM2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Absent in Melanoma 2 (AIM2) (AA 14-215) antibodyAIM2 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
-
- Indications d'application
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- AIM2 (Absent in Melanoma 2 (AIM2))
- Autre désignation
- Aim2 (AIM2 Produits)
- Synonymes
- anticorps AIM2, anticorps PYHIN4, anticorps Gm1313, anticorps Ifi210, anticorps absent in melanoma 2, anticorps AIM2, anticorps Aim2
- Sujet
-
Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2
Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
- ID gène
- 383619
- UniProt
- Q91VJ1
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
-
