GBA anticorps (N-Term)

N° du produit ABIN5514399

Cet anticorps Lapin Polyclonal détecte spécifiquement GBA dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cobaye, Cheval et Lapin.

Aperçu rapide pour GBA anticorps (N-Term) (ABIN5514399)

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GBA anticorps

Épitope: N-Term

Fonction: GBA Antibody - N-terminal region

Séquence: FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS

Homologie: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%

Attributs du produit: This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61323-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur GBA

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Autre désignation: GBA

Sujet:

Background Information: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Gene Name: glucosylceramidase beta

Alternative Symbols: GCB, GBA1, GLUC

Protein Name: glucosylceramidase

Poids moléculaire: 58kDa

ID gène: 2629

NCBI Accession: XP_006711333

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process