Complement Factor B anticorps (N-Term)

N° du produit ABIN5514558

Cet anticorps Lapin Polyclonal détecte spécifiquement Complement Factor B dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Mouton.

Aperçu rapide pour Complement Factor B anticorps (N-Term) (ABIN5514558)

Antigène: Complement Factor B (CFB)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement Factor B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Complement Factor B anticorps

Épitope: N-Term

Séquence: NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CFAB. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFAB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Complement Factor B

Antigène: Complement Factor B (CFB)

Autre désignation: CFAB

Sujet: CFAB is a factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Alias Symbols: CFB, BF, BFD,

Protein Interaction Partner: FN1, LAMC3, RPA2, ALB, CFP, C3,

Protein Size: 764

ID gène: 629

NCBI Accession: NP_001701

UniProt: P00751

Pathways: Système du Complément, Proton Transport, Ribonucleoside Biosynthetic Process