TPP1 anticorps (C-Term)

N° du produit ABIN5514672

Cet anticorps Lapin Polyclonal détecte spécifiquement TPP1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TPP1 anticorps (C-Term) (ABIN5514672)

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TPP1 anticorps

Épitope: C-Term

Séquence: QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TPP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TPP1

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Autre désignation: TPP1

Sujet: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1

Protein Size: 563

ID gène: 1200

NCBI Accession: NM_000391, NP_000382

UniProt: O14773

Pathways: Cycle Cellulaire, ER-Nucleus Signaling