RAB43 anticorps (C-Term)

N° du produit ABIN5515092

Cet anticorps Lapin Polyclonal détecte spécifiquement RAB43 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RAB43 anticorps (C-Term) (ABIN5515092)

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB43 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAB43 anticorps

Épitope: C-Term

Fonction: RAB43 Antibody - C-terminal region

Séquence: ETSAKDSSNV EEAFLRVATE LIMRHGGPLF SEKSPDHIQL NSKDIGEGWG

Attributs du produit: This is a rabbit polyclonal antibody against RAB43. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAB43

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66654-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAB43

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Autre désignation: RAB43

Sujet:

Background Information: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. RAB43 is involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. It plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Alternative Symbols: RAB41, RAB11B

Poids moléculaire: 23 kDa

ID gène: 339122

NCBI Accession: NP_940892

UniProt: Q86YS6