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CAMLG anticorps (C-Term)
CAMLG
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin, Saccharomyces cerevisiae
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5515470
Détail du produit anti-CAMLG anticorps
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Antigène
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CAMLG
(Calcium Modulating Ligand (CAMLG))
Épitope
Tous les épitopes à travers CAMLG Anticorps.
C-Term
Reactivité
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Lapin, Saccharomyces cerevisiae
Hôte
Toutes les hôtes sur CAMLG Anticorps
Lapin
Clonalité
Toutes les clonalités sur CAMLG Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CAMLG Anticorps
Cet anticorp CAMLG est non-conjugé
Application
Tous les applications à travers CAMLG Anticorps.
Western Blotting (WB)
Séquence
LISEKPSQED GNTTEEFDSF RIFRLVGCAL LALGVRAFVC KYLSIFAPFL
Homologie
Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 93%, Yeast: 90%
Attributs du produit
This is a rabbit polyclonal antibody against CAMLG. It was validated on Western Blot.
Purification
Affinity purified
Immunogène
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CAMLG
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur CAMLG
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Antigène
CAMLG
(Calcium Modulating Ligand (CAMLG))
Autre désignation
CAMLG (CAMLG Produits )
Synonymes
anticorps MGC53900, anticorps CAML, anticorps AI385748, anticorps Camlg, anticorps Caml, anticorps calcium modulating ligand L homeolog, anticorps calcium modulating ligand, anticorps camlg.L, anticorps CAMLG, anticorps camlg, anticorps Caml, anticorps Camlg
Sujet
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. Alias Symbols: CAMLG, CAML, Protein Interaction Partner: KCNA2, TMUB1, TNFRSF13B, UBC, RNF122, PKHD1, EGFR, PPIB, IER3, Protein Size: 296
ID gène
819
NCBI Accession
NP_001736
UniProt
P49069
Pathways
EGFR Signaling Pathway
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