CLK2 anticorps (C-Term)

N° du produit ABIN5515887

Cet anticorps Lapin Polyclonal détecte spécifiquement CLK2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour CLK2 anticorps (C-Term) (ABIN5515887)

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CLK2 anticorps

Épitope: C-Term

Séquence: FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CLK2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CLK2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CLK2

Antigène: CLK2 (CDC-Like Kinase 2 (CLK2))

Autre désignation: CLK2

Sujet: This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

Alias Symbols: CLK2,

Protein Interaction Partner: TRIM27, ECE1, CLK3, CLK2, YTHDC1, PRPF38A, LNX1, ZNF394, CPSF7, SNIP1, GMCL1, ZNF398, RSRP1, LUZP4, MRPL4, ZNF473, KLHL2, RNPS1, SRRM1, ZNF263, RBM39, ZRSR2, UBE2I, U2AF1, SRPK2, SDCBP, EED, ZNF30, FIP1L1, LUC7L, ZCCHC8, WDR33, CPSF2, PPHLN1, CPSF1, SETD2

Protein Size: 499

ID gène: 1196

NCBI Accession: XP_005276799

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process