MAPK7 anticorps (N-Term)

N° du produit ABIN5516013

Cet anticorps Lapin Polyclonal détecte spécifiquement MAPK7 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MAPK7 anticorps (N-Term) (ABIN5516013)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPK7 anticorps

Épitope: N-Term

Séquence: PLKEEDGEDG SAEPPGPVKA EPAHTAASVA AKNLALLKAR SFDVTFDVGD

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAPK7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: MAPK7

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Alias Symbols: BMK1, ERK4, ERK5, PRKM7

Protein Size: 816

ID gène: 5598

NCBI Accession: NM_002749, NP_002740

UniProt: Q13164

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling