PAK6 anticorps (C-Term)

N° du produit ABIN5516055

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK6 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Chévre et Cobaye.

Aperçu rapide pour PAK6 anticorps (C-Term) (ABIN5516055)

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Lapin, Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAK6 anticorps

Épitope: C-Term

Séquence: LRDFLERMLV RDPQERATAQ ELLDHPFLLQ TGLPECLVPL IQLYRKQTST

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PAK6. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAK6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PAK6

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Autre désignation: PAK6

Sujet: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Alias Symbols: PAK6, PAK5,

Protein Interaction Partner: RHOJ, RAC1, NEK6, SEMA3B, TPD52L1, SNX2, HSP90AA1, CDK1, MDM2, AR, APP, LNX1, MYC, MAPK14, CDC42, ESR1, AKT1, YWHAQ,

Protein Size: 681

ID gène: 56924

NCBI Accession: NP_064553

UniProt: Q9NQU5