COPS6 anticorps (C-Term)

N° du produit ABIN5516175

Cet anticorps Lapin Polyclonal détecte spécifiquement COPS6 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour COPS6 anticorps (C-Term) (ABIN5516175)

Antigène: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COPS6 anticorps

Épitope: C-Term

Séquence: LILEYVKASE AGEVPFNHEI LREAYALCHC LPVLSTDKFK TDFYDQCNDV

Attributs du produit: This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human COPS6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COPS6

Antigène: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Autre désignation: COPS6

Sujet: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Alias Symbols: Name=COPS6,

Protein Interaction Partner: NEDD8, CUL1, UBC, COPS5, GPS1, SUMO1, POP7, COPS7B, COPS7A, CUL4B, USP7, COPS4, FBXO6, FBXW4, IGHV3OR15-7, vpr, TP63, RFWD2, SFN, IRF5, COPS8, COPS2, COPS3, DDB2, DDB1, ERCC8, TOR1AIP2, LRR1, RBX1, VPRBP, LRRC14, CUL2, CUL3, CUL4A, CUL5, TCEB2, TCEB1, SKP

Protein Size: 327

ID gène: 10980

NCBI Accession: NP_006824

UniProt: Q7L5N1

Pathways: Cycle Cellulaire