CD70 anticorps (C-Term)

N° du produit ABIN5516679

Cet anticorps Lapin Polyclonal détecte spécifiquement CD70 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Porc et Chien.

Aperçu rapide pour CD70 anticorps (C-Term) (ABIN5516679)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD70 anticorps

Épitope: C-Term

Fonction: CD70 Antibody - C-terminal region

Séquence: RLSFHQGCTI ASQRLTPLAR GDTLCTNLTG TLLPSRNTDE TFFGVQWVRP

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 79%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD70

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61308-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70

Sujet:

Background Information: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Name: CD70 Molecule

Alternative Symbols: CD27L, LPFS3, CD27-L, CD27LG, TNFSF7, TNLG8A

Protein Name: CD70 antigen

Poids moléculaire: 21 kDa

ID gène: 970

NCBI Accession: NP_001243

UniProt: P32970

Pathways: Cancer Immune Checkpoints