NSUN2 anticorps (N-Term)

N° du produit ABIN5517213

Cet anticorps Lapin Polyclonal détecte spécifiquement NSUN2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour NSUN2 anticorps (N-Term) (ABIN5517213)

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSUN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NSUN2 anticorps

Épitope: N-Term

Séquence: LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NSUN2. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NSUN2

Antigène: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Autre désignation: NSUN2

Sujet: NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Alias Symbols: NSUN2, SAKI, TRM4,

Protein Interaction Partner: SUMO2, SUMO3, UBC, SUMO1, NEDD8, TP53RK, PUS1, EFTUD1, XPO5, UGGT1, OSGEP, PANK4, THG1L, SH3GLB1, KIAA1279, UBXN7, TTLL12, ARPC2, ACTR2, ACTR3, FUBP1, TSN, SH3GL1, RPA1, RDX, RANGAP1, PPP2CB, PFDN5, PFDN1, NRD1, PPP1R12A, HARS, GTF2E1, CALU, CALR, UBD, VC

Protein Size: 767

ID gène: 54888

NCBI Accession: NP_060225

UniProt: Q08J23