RORC anticorps (N-Term)

N° du produit ABIN5517298

L’anticorps anti-RORC Polyclonal Lapin est utilisé pour la détection de RORC dans des échantillons de Humain, Rat, Cheval, Boeuf (Vache), Porc et Saccharomyces cerevisiae.

Aperçu rapide pour RORC anticorps (N-Term) (ABIN5517298)

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivité: Humain, Rat, Cheval, Boeuf (Vache), Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORC est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-RORC anticorps

Épitope: N-Term

Fonction: RORG Antibody - N-terminal region

Séquence: DSLHAEVQKQ LQQRQQQQQE PVVKTPPAGA QGADTLTYTL GLPDGQLPLG

Homologie: Cow: 92%, Horse: 85%, Human: 100%, Pig: 100%, Rat: 91%, Yeast: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RORG

Information d'application

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59154-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORC

Antigène: RORC (RAR-Related Orphan Receptor C (RORC))

Autre désignation: RORG

Sujet:

Background Information: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: RAR related orphan receptor C

Alternative Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Protein Name: nuclear receptor ROR-gamma

Poids moléculaire: 56 kDa

ID gène: 6097

NCBI Accession: NP_001001523

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway