COBRA1 anticorps (N-Term)

N° du produit ABIN5518104

Cet anticorps Lapin Polyclonal détecte spécifiquement COBRA1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour COBRA1 anticorps (N-Term) (ABIN5518104)

Antigène: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COBRA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COBRA1 anticorps

Épitope: N-Term

Fonction: NELFB Antibody - N-terminal region

Séquence: NCTEPLKAIE QFQTENGVLL PSLQSALPFL DLHGTPRLEF HQSVFDELRD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 90%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human COBRA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65310-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur COBRA1

Antigène: COBRA1 (Cofactor of BRCA1 (COBRA1))

Autre désignation: NELFB

Sujet:

Background Information: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]

Gene Name: negative elongation factor complex member B

Alternative Symbols: COBRA1, NELF-B

Protein Name: negative elongation factor B

Poids moléculaire: 66 kDa

ID gène: 25920

NCBI Accession: NP_056271

UniProt: Q8WX92