JUP anticorps (N-Term)

N° du produit ABIN5518649

Cet anticorps anti-JUP est un anticorps Lapin Polyclonal détectant JUP dans WB, IF, FACS et ICC. Adapté pour Humain.

Aperçu rapide pour JUP anticorps (N-Term) (ABIN5518649)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-JUP anticorps

Épitope: AA 101-118, N-Term

Fonction: Anti-gamma Catenin/JUP Antibody Picoband®

Séquence: LLATQVEGQA TNLQRLAE

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-gamma Catenin/JUP Antibody (ABIN5518649). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human gamma Catenin, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Kolligs, F. T., Kolligs, B., Hajra, K. M., Hu, G., Tani, M., Cho, K. R., Fearon, E. R. : Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331, 2000.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet:

Synonyms: Junction plakoglobin,Catenin gamma,Desmoplakin III,Desmoplakin-3,JUP,CTNNG, DP3,

Tissue Specificity: Widely expressed, with highest levels in heart, brain, and skeletal muscle. .

Background: Cateningamma, also known as junction plakoglobin (JUP) or plakoglobin (PKGB). Plakoglobin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Cateninbeta and cateningamma (plakoglobin), vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Cateningamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Sequence Similarities: Belongs to the beta-catenin family.

Poids moléculaire: 82 kDa

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location