Angiopoietin 1 anticorps (Middle Region)

N° du produit ABIN5518731

Détail du produit anti-Angiopoietin 1 anticorps

Antigène: Angiopoietin 1 (ANGPT1)

Épitope: AA 204-241, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for Angiopoietin-1(ANGPT1) detection. Tested with WB, ELISA in Human.

Séquence: KHKEELDTLK EEKENLQGLV TRQTYIIQEL EKQLNRAT

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Angiopoietin-1(ANGPT1) detection. Tested with WB, ELISA in Human.
Gene Name: angiopoietin 1
Protein Name: Angiopoietin-1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin-1 (204-241aa KHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRAT), different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Angiopoietin 1 (ABIN5518731)

Sun, Wang, Cheng, Wang, Li, Xue, Wang, Ai, Zhang, Xu, Wang, Ji: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." dans: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: ANGPT1 (ANGPT1 Produits)

Synonymes: anticorps AGP1, anticorps AGPT, anticorps ANG1, anticorps 1110046O21Rik, anticorps Ang-1, anticorps Ang1, anticorps Agpt, anticorps Agpt1, anticorps ang1, anticorps wu:fc76g06, anticorps ANG-1, anticorps angpt1, anticorps MGC80788, anticorps angiopoietin 1, anticorps angiopoietin 1 S homeolog, anticorps ANGPT1, anticorps Angpt1, anticorps angpt1, anticorps angpt1.S

Sujet: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Synonyms: ANG-1 | Angiopoietin 1 | Angiopoietin-1 | ANGP1 | ANGPT1 | KIAA0003 | Q15389

ID gène: 284

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process