Angiopoietin 1 anticorps (Middle Region)

N° du produit ABIN5518731

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiopoietin 1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour Angiopoietin 1 anticorps (Middle Region) (ABIN5518731)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: Middle Region

Fonction: Anti-Angiopoietin-1/ANGPT1 Antibody

Séquence: KHKEELDTLK EEKENLQGLV TRQTYIIQEL EKQLNRAT

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by three amino acids,and from the related rat sequence by two amino acids.

Attributs du produit: Anti-Angiopoietin-1/ANGPT1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin-1, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: ELISA, 0.1-0.5 μg/mL, -Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Angiopoietin 1 (ABIN5518731)

Sun, Wang, Cheng, Wang, Li, Xue, Wang, Ai, Zhang, Xu, Wang, Ji: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." dans: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: ANGPT1

Sujet:

Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Gene Full Name: angiopoietin 1

Poids moléculaire: 70 kDa

ID gène: 284

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process