ISL1 anticorps (Middle Region)
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- Antigène Voir toutes ISL1 Anticorps
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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Épitope
- AA 118-161, Middle Region
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ISL1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Insulin gene enhancer protein ISL-1(ISL1) detection. Tested with WB, IHC-P in Human,Rat.
- Séquence
- DEFALREDGL FCRADHDVVE RASLGAGDPL SPLHPARPLQ MAAE
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Insulin gene enhancer protein ISL-1(ISL1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: ISL LIM homeobox 1
Protein Name: Insulin gene enhancer protein ISL-1 - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human Islet 1 (118-161aa DEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAE), identical to the related mouse and rat sequences.
- Isotype
- IgG
- Top Product
- Discover our top product ISL1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- Autre désignation
- ISL1 (ISL1 Produits)
- Synonymes
- anticorps Xisl-1, anticorps Xislet-1, anticorps islet1, anticorps ISLET-1, anticorps ISLET1, anticorps Isl-1, anticorps islet-1, anticorps isl-1=homeobox, anticorps Islet-1, anticorps ISL LIM homeobox 1 S homeolog, anticorps ISL LIM homeobox 1, anticorps ISL1 transcription factor, LIM/homeodomain, anticorps isl1.S, anticorps ISL1, anticorps Isl1, anticorps isl1
- Sujet
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Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Synonyms: ISL 1 | ISL1 | Islet-1 | Islet1 | ISLET1 | P61371 - ID gène
- 3670
- UniProt
- P61371
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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