VSX2 anticorps (AA 249-361)

N° du produit ABIN5518966

L’anticorps Lapin Polyclonal anti-VSX2 a été validé pour WB. Il convient pour détecter VSX2 dans des échantillons de Humain et Souris.

Aperçu rapide pour VSX2 anticorps (AA 249-361) (ABIN5518966)

Antigène: VSX2 (Visual System Homeobox 2 (VSX2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VSX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-VSX2 anticorps

Épitope: AA 249-361

Fonction: Anti-CHX10/VSX2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CHX10/VSX2 Antibody Picoband® (ABIN5518966). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human CHX10 recombinant protein (Position: A249-A361). Human CHX10 shares 90.3% amino acid (aa) sequence identity with mouse CHX10.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Human
1. McInnes, R. R., Basu, S., Novak, J., Ploder, L., Liang, M.-Y., Hawes, N., Taylor, B., Roderick, T., Goldman, D., Hankin, M., Burmeister, M. The ocular retardation (orJ) mouse has an ochre mutation in the homeobox gene Chx10: evidence for Chx10 as a major determinant of retinal development. (Abstract) Am. J. Hum. Genet. 55 (suppl.): A3, 1994. 2. Reichman, S., Kalathur, R. K. R., Lambard, S., Ait-Ali, N., Yang, Y., Lardenois, A., Ripp, R., Poch, O., Zack, D. J., Sahel, J.-A., Leveillard, T. The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina. Hum. Molec. Genet. 19: 250-261, 2010.

Commentaires:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur VSX2

Antigène: VSX2 (Visual System Homeobox 2 (VSX2))

Autre désignation: VSX2

Sujet:

Synonyms: Visual system homeobox 2,Ceh-10 homeodomain-containing homolog,Homeobox protein CHX10,VSX2,CHX10, HOX10,

Tissue Specificity: Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.

Background: Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene. This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. In situ hybridization to human fetal retinal sections detected CHX10 expression in retinal neuroblasts at all stages examined. Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina.

Poids moléculaire: 43 kDa

ID gène: 338917

UniProt: P58304

Pathways: Dopaminergic Neurogenesis