Aurora A anticorps (N-Term)

N° du produit ABIN5530245

L’anticorps anti-Aurora A Polyclonal Lapin est utilisé pour la détection de Aurora A dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour Aurora A anticorps (N-Term) (ABIN5530245)

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Aurora A anticorps

Épitope: AA 93-120, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Aurka antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of mouse Aurka.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Aurora A

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Autre désignation: Aurka

Sujet: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

Poids moléculaire: 45 kDa

ID gène: 20878

UniProt: P97477

Pathways: Cycle Cellulaire, Asymmetric Protein Localization