C4BPB anticorps (AA 125-153)
Aperçu rapide pour C4BPB anticorps (AA 125-153) (ABIN5530978)
Antigène
Voir toutes C4BPB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 125-153
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This C4BPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the Central region of human C4BPB.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.4 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))
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Autre désignation
- C4BPB
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Sujet
- This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
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Poids moléculaire
- 28 kDa
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ID gène
- 725
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UniProt
- P20851
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Pathways
- Système du Complément
Antigène
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