SOCS6 anticorps (N-Term)

N° du produit ABIN5532198

L’anticorps anti-SOCS6 Polyclonal Lapin est utilisé pour la détection de SOCS6 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour SOCS6 anticorps (N-Term) (ABIN5532198)

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SOCS6 anticorps

Épitope: AA 40-69, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SOCS6

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Autre désignation: SOCS6

Sujet: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Poids moléculaire: 60 kDa

ID gène: 9306

UniProt: O14544

Pathways: Signalistation JAK/STAT, Carbohydrate Homeostasis