MLL3 anticorps (N-Term)

N° du produit ABIN5532940

Détail du produit anti-MLL3 anticorps

Antigène: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Épitope: AA 1142-1175, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For IHC-P starting dilution is: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MLL3

Antigène: MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))

Autre désignation: MLL3 (KMT2C Produits)

Synonymes: anticorps HALR, anticorps MLL3, anticorps E330008K23Rik, anticorps Mll3, anticorps mKIAA1506, anticorps lysine methyltransferase 2C, anticorps lysine (K)-specific methyltransferase 2C, anticorps KMT2C, anticorps Kmt2c

Sujet: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Poids moléculaire: 541 kDa

ID gène: 58508

UniProt: Q8NEZ4

Pathways: L'effet Warburg