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IGF1 anticorps (N-Term)

IGF1 Reactivité: Humain WB, IF, FACS, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5534411
  • Antigène Voir toutes IGF1 Anticorps
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Épitope
    • 18
    • 15
    • 15
    • 9
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-77, N-Term
    Reactivité
    • 152
    • 69
    • 60
    • 22
    • 16
    • 9
    • 7
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 130
    • 50
    • 10
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 139
    • 53
    Polyclonal
    Conjugué
    • 96
    • 29
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGF1 est non-conjugé
    Application
    • 145
    • 78
    • 66
    • 56
    • 41
    • 30
    • 27
    • 26
    • 26
    • 20
    • 15
    • 13
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogène
    This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IGF1 Anticorps primaire
  • Indications d'application
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50

    For IF starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Autre désignation
    IGF1 (IGF1 Produits)
    Synonymes
    anticorps IGF-I, anticorps IGF1A, anticorps IGFI, anticorps C730016P09Rik, anticorps Igf-1, anticorps Igf-I, anticorps Npt2B, anticorps IGF-1, anticorps IGFIA, anticorps IGF-IB, anticorps igf1, anticorps IGF-1L, anticorps IGF-1a, anticorps IGF1, anticorps igf-1, anticorps igf1-A, anticorps igf1.S, anticorps xigf1, anticorps insulin like growth factor 1, anticorps insulin-like growth factor 1, anticorps insulin-like growth factor I, anticorps insulin like growth factor 1 L homeolog, anticorps IGF1, anticorps Igf1, anticorps LOC100136741, anticorps igf1, anticorps LOC678666, anticorps igf1.L, anticorps LOC104911603
    Sujet
    The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
    Poids moléculaire
    155 kDa
    ID gène
    3480
    UniProt
    P08069
    Pathways
    Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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