GIP anticorps (AA 104-136)

N° du produit ABIN5535110

Détail du produit anti-GIP anticorps

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Épitope: AA 104-136

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIP est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-136 amino acids from the Central region of human GIPR.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GIP

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Autre désignation: GIP (GIP Produits)

Synonymes: anticorps GIP, anticorps xgip, anticorps Gludins, anticorps RATGLUDINS, anticorps gastric inhibitory polypeptide, anticorps gastric inhibitory polypeptide L homeolog, anticorps GIP, anticorps gip, anticorps Gip, anticorps gip.L

Sujet: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

Poids moléculaire: 53 kDa

ID gène: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism