FZD7 anticorps (AA 202-229)
Aperçu rapide pour FZD7 anticorps (AA 202-229) (ABIN5536129)
Antigène
Voir toutes FZD7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 202-229
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.488 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Autre désignation
- FZD7
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Sujet
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
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Poids moléculaire
- 64 kDa
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ID gène
- 8324
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UniProt
- O75084
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Pathways
- Signalisation WNT, Stem Cell Maintenance
Antigène
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