NME1 anticorps (AA 29-57)
Aperçu rapide pour NME1 anticorps (AA 29-57) (ABIN5537196)
Antigène
Voir toutes NME1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-57
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This NME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the Central region of human NME1.
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Isotype
- Ig Fraction
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Indications d'application
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Autre désignation
- NME1
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Sujet
- This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
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Poids moléculaire
- 17 kDa
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ID gène
- 4830
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UniProt
- P15531
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Pathways
- Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Antigène
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