RAD51C anticorps (AA 169-198)

N° du produit ABIN5537437

Cet anticorps anti-RAD51C est un anticorps Lapin Polyclonal détectant RAD51C dans WB. Adapté pour Humain.

Aperçu rapide pour RAD51C anticorps (AA 169-198) (ABIN5537437)

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAD51C anticorps

Épitope: AA 169-198

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RAD51C

Antigène: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Autre désignation: RAD51C

Sujet: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Poids moléculaire: 42 kDa

ID gène: 5889

UniProt: O43502

Pathways: Réparation de l'ADN