C3 anticorps

N° du produit ABIN5540070

L’anticorps Lapin Polyclonal anti-C3 a été validé pour FACS. Il convient pour détecter C3 dans des échantillons de Porc.

Aperçu rapide pour C3 anticorps (ABIN5540070)

Antigène: C3 (Complement Component 3 (C3))

Reactivité: Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C3 est non-conjugé

Application: Flow Cytometry (FACS)

Détail du produit anti-C3 anticorps

Specificité: The polyclonal antibody recognizes Pig complement component C3.

Purification: Purified

Immunogène: Purified Pig C3

Isotype: Ig Fraction

Information d'application

Indications d'application: Flow Cytometry: Use 1/50 as a typical starting working dilution. Positive Control: Red Blood Cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.02 % Sodium Azide Stabilizers: 0.1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur C3

Antigène: C3 (Complement Component 3 (C3))

Autre désignation: complement c3

Sujet: The complement system is an important part of the humoral response in innate immunity, consisting of three different pathways. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The complement factor C3 consists of an alpha- and a beta-chain. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/mL. An inherited deficiency of C3 predisposes the person to frequent assaults of bacterial infections. In ulcerative colitis, and idiopathic chronic inflammatory bowel disease, the deposition of C3 in the diseased mucosa has been reported. Proteolysis by certain enzymes results in the cleavage of C3 into C3a and C3b. C3b becomes attached to immune complexes and is further cleaved into iC3b, C3c, C3dg and C3f.

UniProt: P01025

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling