TEK anticorps (PE)
Aperçu rapide pour TEK anticorps (PE) (ABIN5540122)
Antigène
Voir toutes TEK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types. Species: Human.
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Purification
- Protein G Chromatography
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Immunogène
- Recombinant human soluble CD202b / TIE-2 protein
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Isotype
- IgG1
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Indications d'application
- FACS analysis and cell sorting: ≤ 0.5 μg/mL in 100 μL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Autre désignation
- cd202b,tek
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Sujet
- TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.
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UniProt
- Q02763
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Pathways
- Signalisation RTK, Growth Factor Binding
Antigène
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