NGFR anticorps (AA 1-160) (Biotin)
Aperçu rapide pour NGFR anticorps (AA 1-160) (Biotin) (ABIN5540156)
Antigène
Voir toutes NGFR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-160
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Specificité
- This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
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Immunogène
- Purified CD271 protein isolated from human melanoma cell line A875
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Isotype
- IgG1
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Indications d'application
- Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.
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Restrictions
- For Research Use only
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Format
- Liquid
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Date de péremption
- 12 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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Autre désignation
- cd271,ngfr
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Sujet
- CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
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UniProt
- P08138
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Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
Antigène
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