CD44 anticorps (PE)

N° du produit ABIN5540180

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS. Il présente une réactivité avec des échantillons de Cheval. Il a été cité dans 3+ publications.

Aperçu rapide pour CD44 anticorps (PE) (ABIN5540180)

Antigène: CD44

Reactivité: Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: CVS18

Détail du produit anti-CD44 anticorps (PE)

Specificité: Clone CVS18 antibody detects equine CD44 and may be used as a pan equine leucocyte marker. Species: Equine (Horse).

Purification: Affinity chromatography on Protein G

Immunogène: Equine leucocytes

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry : Neat, use 10 μL to label 10 6 cells in 100 μL.

Restrictions: For Research Use only

Stockage

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-CD44 (PE) (ABIN5540180)

Carrade, Lame, Kent, Clark, Walker, Borjesson: "Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells()." dans: Cell medicine, Vol. 4, Issue 1, pp. 1-11, (2012) (PubMed).

Radcliffe, Flaminio, Fortier: "Temporal analysis of equine bone marrow aspirate during establishment of putative mesenchymal progenitor cell populations." dans: Stem cells and development, Vol. 19, Issue 2, pp. 269-82, (2010) (PubMed).

Schneider, Essmann, Kletke, Rio, Hanenberg, Wetzel, Schulze-Osthoff, Nürnberg, Piekorz: "The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival." dans: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29273-83, (2007) (PubMed).

Détails sur CD44

Antigène: CD44

Autre désignation: cd44

Sujet: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

UniProt: Q05078

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling