Cathepsin S anticorps (AA 17-331)

N° du produit ABIN5540225

Cet anticorps Souris Monoclonal détecte spécifiquement Cathepsin S dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cathepsin S anticorps (AA 17-331) (ABIN5540225)

Antigène: Cathepsin S (CTSS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin S est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1F9

Détail du produit anti-Cathepsin S anticorps

Épitope: AA 17-331

Specificité: This antibofy recognizes Human CTSS. Other species not tested.

Purification: Affinity Chromatography on Protein A

Immunogène: Recombinant human CTSS (17-331aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution: 1/500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Cathepsin S

Antigène: Cathepsin S (CTSS)

Autre désignation: cathepsin s

Sujet: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

UniProt: P25774

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades