Cyclin H anticorps (AA 1-323)

N° du produit ABIN5540277

L’anticorps anti-Cyclin H Monoclonal Souris est utilisé pour la détection de Cyclin H dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour Cyclin H anticorps (AA 1-323) (ABIN5540277)

Antigène: Cyclin H (CCNH)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT3G6

Détail du produit anti-Cyclin H anticorps

Épitope: AA 1-323

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human Cyclin H (1-323aa) purified from E.coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: cyclin h

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kises. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordition of each mitotic event. This cyclin forms a complex with CDK7 kise and ring finger protein MAT1. The kise complex is able to phosphorylate CDK2 and CDC2 kises, thus functions as a CDK-activating kise (CAK). This cyclin and its kise partner are components of TFIIH, as well as R polymerase II protein complexes. They participate in two different transcriptiol regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.

UniProt: P51946

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase