IL13 Receptor alpha 1 anticorps (Extracellular Domain)

N° du produit ABIN5540414

Cet anticorps Souris Monoclonal détecte spécifiquement IL13 Receptor alpha 1 dans IF, ICC, FACS et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour IL13 Receptor alpha 1 anticorps (Extracellular Domain) (ABIN5540414)

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL13 Receptor alpha 1 est non-conjugé

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: GM1E7

Détail du produit anti-IL13 Receptor alpha 1 anticorps

Épitope: Extracellular Domain

Specificité: Recognizes IL13 Receptor (IL13-R).

Purification: Affinity Chromatography on Protein G

Immunogène: Genetic immunization with cDNA encoding Human IL13-R alpha 1 (extracellular domain). Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.

Isotype: IgG1

Information d'application

Indications d'application: Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. Flow cytometry: 1.2 μg/10 6 cells. Immunofluorescence: 1 μg/10 Specific inhibition of IL-13-dependent proliferation of TF-1 cells by GM-1E7 (See Figure.3).

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL13 Receptor alpha 1

Antigène: IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))

Autre désignation: cd213a1,il13ra1

Sujet: Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Ra1 together with IL-4Ra forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation

UniProt: P78552

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response