Layilin anticorps (AA 22-235)

N° du produit ABIN5540461

Cet anticorps anti-Layilin est un anticorps Souris Monoclonal détectant Layilin dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour Layilin anticorps (AA 22-235) (ABIN5540461)

Antigène: Layilin (LAYN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Layilin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT20G8

Détail du produit anti-Layilin anticorps

Épitope: AA 22-235

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human LAYN (22-235aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Layilin

Antigène: Layilin (LAYN)

Autre désignation: layilin

Sujet: Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.

UniProt: Q6UX15