PAK6 anticorps (pSer560, pSer602)

N° du produit ABIN5541295

Cet anticorps anti-PAK6 est un anticorps Lapin Polyclonal détectant PAK6 dans WB. Adapté pour Humain et Souris.

Aperçu rapide pour PAK6 anticorps (pSer560, pSer602) (ABIN5541295)

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAK6 anticorps

Épitope: pSer560, pSer602

Specificité: The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560.

Purification: Affinity chromatography using epitope-specific peptide

Immunogène: Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6 (KLH-conjugated)

Information d'application

Indications d'application: Western blot: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PAK6

Antigène: PAK6 (P21-Activated Kinase 6 (PAK6))

Autre désignation: pak6

Sujet: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.

UniProt: Q9NQU5