IGF1 anticorps (AA 49-118)

N° du produit ABIN5541323

Cet anticorps Souris Monoclonal détecte spécifiquement IGF1 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour IGF1 anticorps (AA 49-118) (ABIN5541323)

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT6F8

Détail du produit anti-IGF1 anticorps

Épitope: AA 49-118

Specificité: Recognizes Human IGF1. Other species not tested.

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human IGF1 (49-118aa) purified from E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IGF1

Antigène: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Autre désignation: insulin-like growth factor i,igf1

Sujet: Insulin-like growth factor 1(IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene. IGF-1 has also been referred to as a Sulfation factor and its effects were termed nonsuppressible insulin-like activity (NSILA) in the 1970s. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7,649 daltons.

UniProt: P05019

Pathways: Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation